Article
Bicaudal-D is essential for egg chamber formation and cytoskeletal organization in drosophila oogenesis.
Developmental biology - 1 Apr 2001
Oh J, Steward R
Abstract excerpt
Bicaudal-D (Bic-D) is required for the transport of determinant mRNAs and proteins to the presumptive oocyte, an essential step in the differentiation of the oocyte. Bic-D protein contains four well-defined heptad repeat domains characteristic of intermediate filament proteins. We characterized the ovarian phenotypes of females expressing mutant Bic-D proteins (Bic-D(H)) deleted for each of the heptad repeat...
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