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Article

Molecular analysis of the klarsicht gene and its role in nuclear migration within differentiating cells of the Drosophila eye.

Current biology : CB - 4 Nov 1999

Mosley-Bishop K L, Li Q, Patterson L, Fischer J A

Abstract excerpt

BACKGROUND: The temporally regulated, cell-type-specific transport of organelles has great biological significance, yet little is known about the regulation of organelle transport during development. The Drosophila gene klarsicht is required for temporally regulated lipid droplet transport in developing embryos and for the stereotypical nuclear migrations in differentiating cells of the developing eye. Klarsicht...

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PMID: 10556085
DOI: 10.1016/s0960-9822(99)80501-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Molecular analysis of the klarsicht gene and its role in nuclear migration within differentiating cells of the Drosophila eye.PMID 10556085Read ↗

Drosophila klarsicht has distinct subcellular localization domains for nuclear envelope and microtubule localization in the eye.Semantic proximity Read ↗

Organelle-specific control of intracellular transport: distinctly targeted isoforms of the regulator Klar.Semantic proximity Read ↗

Targeting the motor regulator Klar to lipid droplets.Semantic proximity Read ↗

Novel isoforms of the transport regulator klar.Semantic proximity Read ↗

Drosophila klaroid encodes a SUN domain protein required for Klarsicht localization to the nuclear envelope and nuclear migration in the eye.Semantic proximity Read ↗

On the roles of the Drosophila KASH domain proteins Msp-300 and Klarsicht.Semantic proximity Read ↗

BicaudalD actively regulates microtubule motor activity in lipid droplet transport.Semantic proximity Read ↗

Organelle positioning in muscles requires cooperation between two KASH proteins and microtubules.Semantic proximity Read ↗

Localization of Pavarotti-KLP in living Drosophila embryos suggests roles in reorganizing the cortical cytoskeleton during the mitotic cycle.Semantic proximity Read ↗

The Drosophila KASH domain proteins Msp-300 and Klarsicht and the SUN domain protein Klaroid have no essential function during oogenesis.Semantic proximity Read ↗

Kinesin-II is required for axonal transport of choline acetyltransferase in Drosophila.Semantic proximity Read ↗

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