Article
Cannabis receptor haplotype associated with fewer cannabis dependence symptoms in adolescents.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2006
Hopfer Christian J, Young Susan E, Purcell Shaun, Crowley Thomas J, Stallings Michael C, Corley Robin P, Rhee Soo Hyun, Smolen Andrew, Krauter Ken, Hewitt John K, Ehringer Marissa A
Abstract excerpt
Cannabis is a major substance of abuse, and the gene encoding for the central cannabinoid receptor (CNR1) is a logical candidate gene for vulnerability toward developing symptoms of cannabis dependence. We studied four single-nucleotide polymorphisms (SNPs) in the CNR1 gene for association with having one or more symptoms of cannabis dependence in 541 adolescent subjects who had all tried cannabis five or more...
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