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IL-17C/IL-17RE: Emergence of a Unique Axis in TH17 Biology

25 Feb 2020

Abstract excerpt

Therapeutic targeting of IL-17A and its receptor IL-17RA with antibodies has turned out to be a tremendous success in the treatment of several autoimmune conditions. As the IL-17 cytokine family consists of six members (IL-17A to F), it is intriguing to elucidate the biological function of these five other molecules to identify more potential targets. In the past decade, IL-17C has emerged as quite a unique...

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PMID: 32174926
DOI: 10.3389/fimmu.2020.00341

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