Article
Interleukin-2 gene polymorphism in Turkish patients with Behçet's disease and its association with ocular involvement.
International journal of immunogenetics - 1 Oct 2013
Yücel A, Dilek K, Saba D, Ozçimen A A, Yurtkuran M, Oral H B
Abstract excerpt
Behçet's disease (BD) is a chronic immune-mediated systemic disease, characterized by oral and genital lesions and ocular inflammation. Several cytokine genes may play crucial roles in host susceptibility to BD, because the cytokine production capacity varies among individuals and depends on the cytokine gene polymorphisms. The association of the interleukin (IL)-2 gene polymorphisms with the susceptibility to BD...
Topics
- Behcet Syndrome
- DNA
- Eye
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Inflammation
- Interleukin-2
- Lymphocytes
- Male
- Neutrophils
- Polymorphism, Single Nucleotide
- Turkey
