Article
Association of TLR4 polymorphisms with Behcet's disease in a Korean population.
Rheumatology (Oxford, England) - 1 Jun 2009
Horie Yukihiro, Meguro Akira, Ota Masao, Kitaichi Nobuyoshi, Katsuyama Yoshihiko, Takemoto Yuko, Namba Kenichi, Yoshida Kazuhiko, Song Yeong Wook, Park Kyung Sook, Lee Eun Bong, Inoko Hidetoshi, Mizuki Nobuhisa, Ohno Shigeaki
Abstract excerpt
OBJECTIVES: HLA-B51 is strongly associated with Behçet's disease (BD) in any ethnic background. We recently reported that another gene, Toll-like receptor-4 (TLR4) is also implicated in BD in a Japanese population. To confirm these results, we investigated polymorphisms in the TLR4 gene in Korean patients with BD. METHODS: In this study, 119 patients with BD and 141 healthy controls were enrolled; every...
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