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Article

Methodology to probe subunit interactions in ribonucleotide reductases.

Biochemistry - 9 Dec 2008

Hassan A Quamrul, Wang Yongting, Plate Lars, Stubbe JoAnne

Abstract excerpt

Ribonucleotide reductases (RNRs) catalyze the conversion of nucleotides to deoxynucleotides, providing the monomeric precursors required for DNA replication and repair. Escherichia coli RNR is a 1:1 complex of two homodimeric subunits, alpha2 and beta2. The interactions between alpha2 and beta2 are thought to be largely associated with the C-terminal 20 amino acids (residues 356-375) of beta2. To study subunit...

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PMID: 19012414
DOI: 10.1021/bi8012559
PMCID: PMC2645937

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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