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Article

PPARgamma gene C161T substitution is associated with reduced risk of coronary artery disease and decreased proinflammatory cytokine expression.

American heart journal - 1 Oct 2007

Liu Yu, Yuan Zuyi, Liu Yan, Zhang Jijun, Yin Ping, Wang Dongqi, Wang Yanni, Kishimoto Chiharu, Ma Aiqun

Abstract excerpt

BACKGROUND: Peroxisome proliferator-activated receptor gamma (PPARgamma) is a transcription factor implicated in the expression of proinflammatory cytokines in atheroma-associated cells, and the expression of proinflammatory cytokines, such as tumor necrosis factor alpha (TNF-alpha) and matrix metalloproteinases (MMPs), represents a critical step in atherogenesis and atherosclerosis. In this study, we test the...

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Identifiers

PMID: 17892998
DOI: 10.1016/j.ahj.2007.06.009

Genes

CAD
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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