Article
The Asp(327)Asn polymorphism in the sex hormone-binding globulin gene modifies the association of soy food and tea intake with endometrial cancer risk.
Nutrition and cancer - 1 Jan 2008
Xu Wang Hong, Zheng Wei, Cai Qiuyin, Cheng Jia-Rong, Cai Hui, Xiang Yong-Bing, Shu Xiao Ou
Abstract excerpt
We evaluated the interactive effect of polymorphisms in the sex hormone-binding globulin (SHBG) gene with soy isoflavones, tea consumption, and dietary fiber on endometrial cancer risk in a population-based, case-control study of 1,199 endometrial cancer patients and 1,212 controls. Genotyping of polymorphisms was performed by using TaqMan (Applied Biosystems, Foster City, CA) assays (rs6259) or the Affymetrix...
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