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Article

Drosophila Activin- and the Activin-like product Dawdle function redundantly to regulate proliferation in the larval brain.

Development (Cambridge, England) - 1 Feb 2008

Zhu Changqi C, Boone Jason Q, Jensen Philip A, Hanna Scott, Podemski Lynn, Locke John, Doe Chris Q, O'Connor Michael B

Abstract excerpt

The Drosophila Activin-like ligands Activin-beta and Dawdle control several aspects of neuronal morphogenesis, including mushroom body remodeling, dorsal neuron morphogenesis and motoneuron axon guidance. Here we show that the same two ligands act redundantly through the Activin receptor Babo and its transcriptional mediator Smad2 (Smox), to regulate neuroblast numbers and proliferation rates in the developing...

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Identifiers

PMID: 18171686
DOI: 10.1242/dev.010876

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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