Article
Mycobacterium-specific human CD8 T cell responses.
Archivum immunologiae et therapiae experimentalis - 1 Jan 2001
Klein M R, Fox A
Abstract excerpt
Tuberculosis (TB) remains a global health problem. There is an intense effort to identify correlates of protective immunity and to design new TB vaccines. CD8 T cells are thought to play a significant role in controlling Mycobacterium tuberculosis infection. Relatively little has been published about the antigens and epitopes targeted by mycobacteria-specific CD8 T cells. Here we present an update of our 1999...
Topics
- Amino Acid Sequence
- Animals
- Antigens, Bacterial
- BCG Vaccine
- CD8-Positive T-Lymphocytes
- Disease Models, Animal
- Epitopes
- Genetic Variation
- Humans
- Immunologic Tests
- In Vitro Techniques
- Molecular Sequence Data