Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The presence of the CYP11A1 (TTTTA)6 allele increases the risk of biochemical relapse in organ confined and low-grade prostate cancer.

Cancer genetics and cytogenetics - 1 Nov 2008

Celhar Teja, Gersak Ksenija, Ovcak Zdenka, Sedmak Boris, Mlinaric-Rascan Irena

Abstract excerpt

The involvement of the CYP11A1 gene in the synthesis of androgens makes it a compelling candidate for various hormone-dependent diseases, including prostate cancer. A microsatellite polymorphism (TTTTA)n in the promoter region of the CYP11A1 gene has been reported to be associated with an increased risk of metastatic and high-grade prostate cancer. In the present study of 110 prostate cancer patients and 96...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholesterol Side-Chain Cleavage Enzyme
Share to Microsatellite Repeats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymerase Chain Reaction

Share to Prostatic Neoplasms

Share to Recurrence

Share to Reference Values

Share to Risk Factors

Share to Slovenia

Source

Identifiers

PMID: 18992638
DOI: 10.1016/j.cancergencyto.2008.08.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The presence of the CYP11A1 (TTTTA)6 allele increases the risk of biochemical relapse in organ confined and low-grade prostate cancer.PMID 18992638Read ↗

Impact of Matrix Metalloproteinase-11 Gene Polymorphisms on Biochemical Recurrence and Clinicopathological Characteristics of Prostate Cancer.Semantic proximity Read ↗

Clinical significance of runt-related transcription factor 1 polymorphism in prostate cancer.Semantic proximity Read ↗

Glutathione-S-transferase (GST) polymorphisms are associated with relapse after radical prostatectomy.Semantic proximity Read ↗

The CYP19A1 (TTTA)n Repeat Polymorphism May Affect the Prostate Cancer Risk: Evidence from a Meta-Analysis.Semantic proximity Read ↗

An MGMT Allelic Variant Can Affect Biochemical Relapse in Prostate Cancer Patients.Semantic proximity Read ↗

Association of HSD3B1 Genotype With Response to Androgen-Deprivation Therapy for Biochemical Recurrence After Radiotherapy for Localized Prostate Cancer.Semantic proximity Read ↗

SRD5A polymorphisms and biochemical failure after radical prostatectomy.Semantic proximity Read ↗

Androgen receptor polymorphisms: association with prostate cancer risk, relapse and overall survival.Semantic proximity Read ↗

Improved prediction of biochemical recurrence after radical prostatectomy by genetic polymorphisms.Semantic proximity Read ↗

Genetic variants of the CYP1B1 gene as predictors of biochemical recurrence after radical prostatectomy in localized prostate cancer patients.Semantic proximity Read ↗

Genetic variants in microRNAs and microRNA target sites predict biochemical recurrence after radical prostatectomy in localized prostate cancer.Semantic proximity Read ↗

Genetic variants of ADAM9 as potential predictors for biochemical recurrence in prostate cancer patients after receiving a radical prostatectomy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.