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Article

Genetic variants of ADAM9 as potential predictors for biochemical recurrence in prostate cancer patients after receiving a radical prostatectomy.

International journal of medical sciences - 1 Jan 2024

Lin Yung-Wei, Wen Yu-Ching, Lin Chia-Yen, Hsiao Chi-Hao, Ho Kuo-Hao, Huang Hsiang-Ching, Chang Lun-Ching, Wang Shian-Shiang, Yang Shun-Fa, Chien Ming-Hsien

Abstract excerpt

A disintegrin and metalloproteinase domain-containing protein 9 (ADAM9) functions as a membranous bridge, forming cell-cell and cell-matrix connections that regulate tumor aggressiveness in various cancer types, including prostate cancer (PCa). Elevated ADAM9 levels in PCa were identified as a prognostic marker for biochemical recurrence (BCR) in patients who had undergone a radical prostatectomy (RP). However,...

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Identifiers

PMID: 39628685
DOI: 10.7150/ijms.103179
PMCID: PMC11610326

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