Article
Genetic variants in microRNAs and microRNA target sites predict biochemical recurrence after radical prostatectomy in localized prostate cancer.
International journal of cancer - 1 Dec 2014
Huang Shu-Pin, Lévesque Eric, Guillemette Chantal, Yu Chia-Cheng, Huang Chao-Yuan, Lin Victor C, Chung I-Che, Chen Lih-Chyang, Laverdière Isabelle, Lacombe Louis, Fradet Yves, Chang Ta-Yuan, Lee Hong-Zin, Juang Shin-Hun, Bao Bo-Ying
Abstract excerpt
Recent evidence indicates that microRNAs might participate in prostate cancer initiation, progression and treatment response. Germline variations in microRNAs might alter target gene expression and modify the efficacy of prostate cancer therapy. To determine whether genetic variants in microRNAs and microRNA target sites are associated with the risk of biochemical recurrence (BCR) after radical prostatectomy...
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