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Article

TCR-beta chains derived from peripheral gammadelta T cells can take part in alphabeta T-cell development.

European journal of immunology - 1 Dec 2008

Bosco Nabil, Engdahl Corinne, Bénard Angèle, Rolink Johanna, Ceredig Rhodri, Rolink Antonius G

Abstract excerpt

Between 10 and 20% of the peripheral gammadelta T cells express cytoplasmic TCR-beta proteins, but whether such TCR-beta chains can partake in alphabeta T-cell development has never been systematically investigated. Therefore, we reconstituted the T-cell compartment of CD3epsilon-deficient mice with Pax5-TCR-beta deficient proB cells expressing, via a retroviral vector, TCR-beta chains from either peripheral...

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Source

Identifiers

PMID: 18991270
DOI: 10.1002/eji.200838668

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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