Article
Interleukin13 haplotypes and susceptibility of Iranian women to breast cancer.
Molecular biology reports - 1 Sept 2009
Faghih Zahra, Erfani Nasrollah, Razmkhah Mahboobeh, Sameni Safoura, Talei Abdolrasoul, Ghaderi Abbas
Abstract excerpt
Interleukin-13 (IL-13) is a TH2 cytokine with direct and indirect immunoregulatory functions on cancer cells. The cytokine has been reported to have some polymorphic variations at the gene level associated with some immune related diseases including asthma and allergy. In the present study, association of three IL13 gene polymorphisms at positions -1512 A/C and -1055 C/T in the promoter and +2044 G/A in exon-4...
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