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Article

Catecholamine uptake, melanization, and oxygen toxicity in Cryptococcus neoformans.

Journal of bacteriology - 1 Jan 1991

Jacobson E S, Emery H S

Abstract excerpt

Oxygen sensitivity mutations of Cryptococcus neoformans were mapped to three genetic loci. Three oxygen-sensitive mutants had mutations that appeared allelic and exhibited albinism tightly linked to oxygen sensitivity; these three and a fourth exhibited defects in catechol uptake and catechol oxidation to melanin. Catecholamine metabolism appears to protect C. neoformans from oxidants.

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Source

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Identifiers

PMID: 1898925
DOI: 10.1128/jb.173.1.401-403.1991
PMCID: PMC207201

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Catecholamine uptake, melanization, and oxygen toxicity in Cryptococcus neoformans.PMID 1898925Read ↗

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Melanin and virulence in Cryptococcus neoformansSemantic proximity Read ↗

Melanin-deficient mutants of<i>Cryptococcus neoformans</i>Semantic proximity Read ↗

The interplay between electron transport chain function and iron regulatory factors influences melanin formation in <i>Cryptococcus neoformans</i>Semantic proximity Read ↗

Relationship between superoxide dismutase and melanin in a pathogenic fungus.Semantic proximity Read ↗

Antioxidant function of fungal melanin.Semantic proximity Read ↗

Distinct stress responses of two functional laccases in Cryptococcus neoformans are revealed in the absence of the thiol-specific antioxidant Tsa1.Semantic proximity Read ↗

Oxy2 as a transcriptional activator gene for copper uptake in Cryptococcus neoformans.Semantic proximity Read ↗

Iron assimilation in Cryptococcus neoformans.Semantic proximity Read ↗

Oxygen induces mutation in a strict anaerobe, Prevotella melaninogenica.Semantic proximity Read ↗

Melanization affects susceptibility of Cryptococcus neoformans to heat and cold1Semantic proximity Read ↗

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