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Article

Relationship between superoxide dismutase and melanin in a pathogenic fungus.

Infection and immunity - 1 Sept 1994

Jacobson E S, Jenkins N D, Todd J M

Abstract excerpt

Since melanin is considered a virulence factor in Cryptococcus neoformans, its suppression at 37 degrees C has been perplexing. We now show an opposite thermal regulation of superoxide dismutase (SOD), consistent with a compensatory mechanism. Moreover, we demonstrate normal SOD and catalase levels in albino, oxygen-sensitive mutants. These results suggest that melanin is an antioxidant factor comparable in...

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Source

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Identifiers

PMID: 8063430
DOI: 10.1128/iai.62.9.4085-4086.1994
PMCID: PMC303074

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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