Article
Iron assimilation in Cryptococcus neoformans.
Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology - 1 Jan 1992
Jacobson E S, Vartivarian S E
Abstract excerpt
We studied the effects of iron chelators and of a thallium salt on growth of Cryptococcus neoformans in defined medium. An oxidant-sensitive mutant strain was found to require exogenous ferric iron for growth. Using this strain, we found that the synthetic iron chelator, N-hydroxyethylenediamine triacetate (HEDTA), in several saturation states, stimulated growth as well as the comparably saturated siderophore...
Topics
- Biological Transport
- Catechols
- Cryptococcus neoformans
- Iron
- Iron Chelating Agents
- Mutation
- Oxidation-Reduction
- Thallium