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Article

Quercetin activates human Kv1.5 channels by a residue I502 in the S6 segment.

Clinical and experimental pharmacology & physiology - 1 Feb 2009

Yang Lan, Ma Ji-Hua, Zhang Pei-Hua, Zou An-Ruo, Tu Dan-Na

Abstract excerpt

1. The aims of the present study were to investigate the pharmacological effects of quercetin on wild-type (WT) and mutant (I502A) human (h) Kv1.5 channel currents (I(kur)) and to identify whether mutation in the S6 segment is critical to activation of I(kur) by quercetin. 2. Experiments were performed on WT and site-directed mutant hKv1.5 channels, which were stably expressed in Xenopus oocytes using the...

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Identifiers

PMID: 18986330
DOI: 10.1111/j.1440-1681.2008.05061.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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