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A clone screening method using mRNA levels to determine specific productivity and product quality for monoclonal antibodies

17 Sept 2008

Abstract excerpt

To meet increasing demands for efficient and streamlined production processes of therapeutic antibodies, improved methods of screening clones are required. In this article, we examined the potential of using antibody transcript levels as criteria for clone screening. We evaluated the QuantiGene Plex, a commercially available, high-throughput assay for simultaneously measuring multiple transcripts from cell...

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PMID: 18985612
DOI: 10.1002/bit.22126

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