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Article

Cell volume as a factor limiting the replicative lifespan of the yeast Saccharomyces cerevisiae.

Biogerontology - 1 Aug 2009

Zadrag-Tecza Renata, Kwolek-Mirek Magdalena, Bartosz Grzegorz, Bilinski Tomasz

Abstract excerpt

The number of cell divisions of the yeast Saccharomyces cerevisiae is limited, referred to as "replicative lifespan" of this organism and believed to be due to aging mechanisms similar to those of mammalian cells. We demonstrate, using three pairs of isogenic yeast strains (standard and a mutant deficient in an antioxidant defense protein) that although the lifespan differs significantly, the final volume...

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PMID: 18985429
DOI: 10.1007/s10522-008-9192-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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