Article
A mother's sacrifice: what is she keeping for herself?
Current opinion in cell biology - 1 Dec 2008
Henderson Kiersten A, Gottschling Daniel E
Abstract excerpt
Individual cells of the budding yeast, Saccharomyces cerevisiae, have a limited life span and undergo a form of senescence termed replicative aging. Replicative life span is defined as the number of daughter cells produced by a yeast mother cell before she ceases dividing. Replicative aging is asymmetric: a mother cell ages but the age of her daughter cells is 'reset' to zero. Thus, one or more senescence factors...
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