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Article

Analysis of the IDH1 codon 132 mutation in brain tumors.

Acta neuropathologica - 1 Dec 2008

Balss Jörg, Meyer Jochen, Mueller Wolf, Korshunov Andrey, Hartmann Christian, von Deimling Andreas

Abstract excerpt

A recent study reported on mutations in the active site of the isocitrate dehydrogenase (IDH1) gene in 12% of glioblastomas. All mutations detected resulted in an amino acid exchange in position 132. We analyzed the genomic region spanning wild type R132 of IDH1 by direct sequencing in 685 brain...

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Source

Identifiers

PMID: 18985363
DOI: 10.1007/s00401-008-0455-2

Genes

IDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18985363-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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