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Article

Species-Specific Interaction of Streptococcus pneumoniae with Human Complement Factor H

1 Nov 2008

Abstract excerpt

Streptococcus pneumoniae naturally colonizes the nasopharynx as a commensal organism and sometimes causes infections in remote tissue sites. This bacterium is highly capable of resisting host innate immunity during nasopharyngeal colonization and disseminating infections. The ability to recruit complement factor H (FH) by S. pneumoniae has been implicated as a bacterial immune evasion mechanism against...

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Identifiers

PMID: 18981135
DOI: 10.4049/jimmunol.181.10.7138

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