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Article

Functional analysis of six different polymorphic CYP1B1 enzyme variants found in an Ethiopian population.

Molecular pharmacology - 1 Mar 2002

Aklillu Eleni, Oscarson Mikael, Hidestrand Mats, Leidvik Brith, Otter Charlotta, Ingelman-Sundberg Magnus

Abstract excerpt

Cytochrome P450 1B1 (CYP1B1) is an extrahepatic enzyme of potential importance for the metabolism of estrogen and for metabolic activation of environmental carcinogens. We investigated an Ethiopian population for functional polymorphisms in the CYP1B1 gene using genomic DNA sequencing and detected three novel single nucleotide polymorphisms (SNPs). One of these (4360C-->G in exon 3) is present at a frequency of...

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Identifiers

PMID: 11854439
DOI: 10.1124/mol.61.3.586

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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