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Article

Crystal structures of human BTG2 and mouse TIS21 involved in suppression of CAF1 deadenylase activity.

Nucleic acids research - 1 Dec 2008

Yang Xiuna, Morita Masahiro, Wang Hui, Suzuki Toru, Yang Wen, Luo Yunhai, Zhao Cong, Yu Yue, Bartlam Mark, Yamamoto Tadashi, Rao Zihe

Abstract excerpt

BTG2 is the prototypical member of the TOB family and is known to be involved in cell growth, differentiation and DNA repair. As a transcriptional co-regulator, BTG2 interacts with CCR4-associated factor 1 (CAF1) and POP2 (CALIF), which are key components of the general CCR4/NOT multi-subunit tra...

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Source

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Identifiers

PMID: 18974182
DOI: 10.1093/nar/gkn825
PMCID: PMC2588512

Genes

BTG2
CCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18974182-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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