Article
Risk of gynecologic cancers in Danish hereditary non-polyposis colorectal cancer families.
Acta obstetricia et gynecologica Scandinavica - 1 Jan 2008
Boilesen Astrid Elisabeth Bruun, Bisgaard Marie Luise, Bernstein Inge
Abstract excerpt
OBJECTIVE: Women in hereditary non-polyposis colorectal cancer (HNPCC) families have an elevated risk of endometrial and ovarian cancer. The risk in Lynch syndrome families with known mutations in mismatch repair genes (MMR genes) seems to be higher than in familial colorectal cancer (CRC) families. Data in the Danish HNPCC register on the frequency and lifetime risk of gynecologic cancers were analyzed and the...
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