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Article

High risk of endometrial cancer in colorectal cancer kindred is pathognomonic for MMR-mutation carriers.

Familial cancer - 1 Jan 2009

Grindedal Eli Marie, Blanco Ignacio, Stormorken Astrid, Maehle Lovise, Clark Neal, González Sara, Capella Gabriel, Vasen Hans, Burn John, Møller Pål

Abstract excerpt

Endometrial cancer is frequent in MMR-mutation carriers. Estimates of annual incidence rates have, however, been based on retrospective studies. The purpose of our study was to prospectively assess the incidence rates of endometrial cancer in women either having a mutation in one of the four MMR genes MLH1, MSH2, MSH6 or PMS2 (Mut+) or belonging to families meeting the revised Amsterdam criteria in which no MMR...

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Source

Identifiers

PMID: 18841495
DOI: 10.1007/s10689-008-9219-3

Genes

MLH1
MSH2
MSH6
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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