Frequency of Hereditary Non-Polyposis Colorectal Cancer among Unselected Patients with Colorectal Cancer in Germany

doi:10.1159/000096868

Article

Frequency of Hereditary Non-Polyposis Colorectal Cancer among Unselected Patients with Colorectal Cancer in Germany

1 Jan 2006

Abstract excerpt

INTRODUCTION: Hereditary non-polyposis colorectal cancer (HNPCC) is a major form of familial colorectal cancer (CRC). It is diagnosed when either the Amsterdam criteria (AC) are fulfilled or mutations in one of the mismatch repair (MMR) genes have been identified. This project aims at estimating the proportion of HNPCC among unselected patients with CRC. PATIENTS AND METHODS: During a period of 2 years, a total...

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