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Article

Masculinization of XX Drosophila transgenic flies expressing the Ceratitis capitata DoublesexM isoform.

The International journal of developmental biology - 1 Jan 2008

Saccone Giuseppe, Salvemini Marco, Pane Attilio, Polito Lino C

Abstract excerpt

The Doublesex (DSX) transcription factor regulates somatic sexual differentiation in Drosophila melanogaster. Female and male isoforms (DSXF and DSXM) are produced due to sex-specific RNA splicing. Here we show that in the distantly related dipteran Ceratitis capitata, the DSXM male-specific isoform is conserved and able to induce masculinization of both somatic and germline tissues when ectopically expressed in...

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Identifiers

PMID: 18956338
DOI: 10.1387/ijdb.082657gs

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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