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Article

Sex determination in the Drosophila germline is dictated by the sexual identity of the surrounding soma.

Genetics - 1 Aug 2000

Waterbury J A, Horabin J I, Bopp D, Schedl P

Abstract excerpt

It has been suggested that sexual identity in the germline depends upon the combination of a nonautonomous somatic signaling pathway and an autonomous X chromosome counting system. In the studies reported here, we have examined the role of the sexual differentiation genes transformer (tra) and doublesex (dsx) in regulating the activity of the somatic signaling pathway. We asked whether ectopic somatic expression...

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Identifiers

PMID: 10924471
DOI: 10.1093/genetics/155.4.1741
PMCID: PMC1461178

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