Article
Mutation of doublesex in Hyphantria cunea results in sex-specific sterility.
Pest management science - 1 May 2020
Li Xiaowei, Liu Qun, Liu Huihui, Bi Honglun, Wang Yaohui, Chen Xien, Wu Ningning, Xu Jun, Zhang Zhen, Huang Yongping, Chen Hui
Abstract excerpt
BACKGROUND: The gene doublesex (dsx) plays pivotal roles in sex determination and controls sexually dimorphic development in certain insects. Importantly, it also displays a potential candidate target for pest management due to its sex-specific splicing. Therefore, we used CRISPR/Cas9-mediated gene disruption to investigate the function of dsx in Hyphantria cunea, an invasive forest pest. RESULT: In the present...
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