Neuroattenuation of an avirulent bunyavirus variant maps to the L RNA segment.

doi:10.1128/JVI.65.10.5465-5470.1991

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Article

Neuroattenuation of an avirulent bunyavirus variant maps to the L RNA segment.

Journal of virology - 1 Oct 1991

Endres M J, Griot C, Gonzalez-Scarano F, Nathanson N

Abstract excerpt

The derivation and characterization of a neuroattenuated reassortant clone (RFC 25/B.5) of California serogroup bunyavirus was described previously (M. J. Endres, A. Valsamakis, F. Gonzalez-Scarano, and N. Nathanson, J. Virol. 64:1927-1933, 1990). To map the RNA segment responsible for this atten...

Topics

Animals
Brain
Cell Line
Encephalitis Virus, California
Encephalitis, California
Genetic Variation
Genotype
Mice
Phenotype
Viral Plaque Assay
Virulence
Virus Replication

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