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Article

Neuroattenuation of an avirulent bunyavirus variant maps to the L RNA segment.

Journal of virology - 1 Oct 1991

Endres M J, Griot C, Gonzalez-Scarano F, Nathanson N

Abstract excerpt

The derivation and characterization of a neuroattenuated reassortant clone (RFC 25/B.5) of California serogroup bunyavirus was described previously (M. J. Endres, A. Valsamakis, F. Gonzalez-Scarano, and N. Nathanson, J. Virol. 64:1927-1933, 1990). To map the RNA segment responsible for this attenuation, a panel of reassortants was constructed between the attenuated clone B.5 (genotype TLL) and a virulent clone...

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Identifiers

PMID: 1895395
DOI: 10.1128/JVI.65.10.5465-5470.1991
PMCID: PMC249038

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