Article
Immunogenicity and cross-protective efficacy induced by delayed attenuated Salmonella with regulated length of lipopolysaccharide in mice.
Gut microbes - 1 Jan 2024
Bian Xiaoping, Liu Qing, Chen Yaolin, Zhang Wenjin, Li Mengru, Zhang Xiaofen, Yang Liu, Liao Yonghong, Kong Qingke
Abstract excerpt
Non-typhoidal Salmonella enterica (NTS) is a major global foodborne pathogen that poses a major public health concern worldwide, and no vaccines are available for protecting against infection of multiple Salmonella serotypes, therefore, the development of Salmonella vaccines to provide broad protection is valuable. In this work, we aimed to regulate lipopolysaccharide (LPS) synthesis of live Salmonella in vivo...
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