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Article

Emergence of drug-resistant influenza virus: population dynamical considerations.

Science (New York, N.Y.) - 21 Apr 2006

Regoes Roland R, Bonhoeffer Sebastian

Abstract excerpt

Given the considerable challenges to the rapid development of an effective vaccine against influenza, antiviral agents will play an important role as a first-line defense if a new pandemic occurs. The large-scale use of drugs for chemoprophylaxis and treatment will impose strong selection for the evolution of drug-resistant strains. The ensuing transmission of those strains could substantially limit the...

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Identifiers

PMID: 16627735
DOI: 10.1126/science.1122947

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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