Article
Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study.
Gynecologic oncology - 1 Jan 2009
Vega Ana, Salas Antonio, Milne Roger L, Carracedo Begoña, Ribas Gloria, Ruibal Alvaro, de León Antonio Cabrera, González-Hernández Ana, Benítez Javier, Carracedo Angel
Abstract excerpt
OBJECTIVES: A polygenic model has been proposed in order to explain the genetic susceptibility to sporadic breast cancer. According to this model, common population variants would be responsible for low to modest effects on the risk of developing the disease. We have carried out a high-throughput...
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