Article
Discovering interactions among BRCA1 and other candidate genes associated with sporadic breast cancer.
Proceedings of the National Academy of Sciences of the United States of America - 26 Aug 2008
Lo Shaw-Hwa, Chernoff Herman, Cong Lei, Ding Yuejing, Zheng Tian
Abstract excerpt
Analysis of a subset of case-control sporadic breast cancer data, [from the National Cancer Institute's Cancer Genetic Markers of Susceptibility (CGEMS) initiative], focusing on 18 breast cancer-related genes with 304 SNPs, indicates that there are many interesting interactions that form two- and three-way networks in which BRCA1 plays a dominant and central role. The apparent interactions of BRCA1 with many...
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