Article
A spectraplakin is enriched on the fusome and organizes microtubules during oocyte specification in Drosophila.
Current biology : CB - 20 Jan 2004
Röper Katja, Brown Nicholas H
Abstract excerpt
BACKGROUND: During Drosophila oogenesis a membranous organelle called the fusome has a key function in the establishment of oocyte fate and polarity, ultimately leading to the establishment of the major body axes of the animal. The fusome is necessary for the microtubule-driven restriction of markers of oocyte fate to the oocyte, but the mechanism by which the fusome organizes the microtubules is not known....
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