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Article

Multiple interactions between the alpha 2C- and beta1-adrenergic receptors influence heart failure survival.

BMC medical genetics - 23 Oct 2008

Kardia Sharon L R, Kelly Reagan J, Keddache Mehdi A, Aronow Bruce J, Grabowski Gregory A, Hahn Harvey S, Case Karen L, Wagoner Lynne E, Dorn Gerald W, Liggett Stephen B

Abstract excerpt

BACKGROUND: Persistent stimulation of cardiac beta1-adrenergic receptors by endogenous norepinephrine promotes heart failure progression. Polymorphisms of this gene are known to alter receptor function or expression, as are polymorphisms of the alpha 2C-adrenergic receptor, which regulates norepi...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Adrenergic, alpha-2

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Source

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Identifiers

PMID: 18947427
DOI: 10.1186/1471-2350-9-93
PMCID: PMC2588439

Genes

ADRB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18947427-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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