Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of a lymphotoxin-alpha gene polymorphism and atopic asthma in Taiwanese children.

Pediatrics and neonatology - 1 Apr 2008

Huang Szu-Chao, Wu Wen-Jun, Sun Hai-Lun, Lue Ko-Huang, Hsu Chia-Hsiu, Liao Pei-Fen, Ku Min-Sho

Abstract excerpt

BACKGROUND: The lymphotoxin-alpha (LT-alpha) gene is located on chromosome 6 (6p21.1-6p21.3) and it may regulate tumor necrosis factor (TNF) production. TNF is a potent cytokine in the airway inflammatory response. Polymorphisms of TNF-associated genes have been related to asthma. This study investigated an LT-alpha-Ncol polymorphism in the first intron of the LT-alpha gene (LT-alpha-Ncol*1 allele, as a variant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Asthma
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to TNF gene

Share to Genotype

Share to Lymphotoxin-alpha

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 18947013
DOI: 10.1016/S1875-9572(08)60008-X

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of a lymphotoxin-alpha gene polymorphism and atopic asthma in Taiwanese children.PMID 18947013Read ↗

Gene-gene synergistic effect on atopic asthma: tumour necrosis factor-alpha-308 and lymphotoxin-alpha-NcoI in Taiwan's children.Semantic proximity Read ↗

Association of a lymphotoxin alpha gene polymorphism and atopy in Italian families.Semantic proximity Read ↗

Relation between tumour necrosis factor polymorphism TNFalpha-308 and risk of asthma.Semantic proximity Read ↗

Haplotype analysis of a 100 kb region spanning TNF-LTA identifies a polymorphism in the LTA promoter region that is associated with atopic asthma susceptibility in Japan.Semantic proximity Read ↗

Association of polymorphisms within the tumour necrosis factor (TNF) genes and childhood asthma.Semantic proximity Read ↗

Extended haplotype in the tumor necrosis factor gene cluster is associated with asthma and asthma-related phenotypes.Semantic proximity Read ↗

Polymorphisms in the IL-4, IL-4 receptor alpha chain, TNF-alpha, and lymphotoxin-alpha genes and risk of asthma in Hong Kong Chinese adults.Semantic proximity Read ↗

The +252A/G polymorphism in the lymphotoxin-α gene increases the risk of asthma: a meta-analysis.Semantic proximity Read ↗

Tumor Necrosis Factor-α (-308G>A) Gene Polymorphism and Its Association with Asthma and Atopy Status.Semantic proximity Read ↗

TNFA -308G>A in two international population-based cohorts and risk of asthma.Semantic proximity Read ↗

Association of TNF haplotypes with asthma, serum IgE levels, and correlation with serum TNF-alpha levels.Semantic proximity Read ↗

Parental smoking modifies the relation between genetic variation in tumor necrosis factor-alpha (TNF) and childhood asthma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.