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Article

Polymorphisms in the IL-4, IL-4 receptor alpha chain, TNF-alpha, and lymphotoxin-alpha genes and risk of asthma in Hong Kong Chinese adults.

International archives of allergy and immunology - 1 Jan 2007

Mak Judith C W, Ko Fanny W S, Chu Chung M, Leung Helen C M, Chan Henry W, Cheung Amy H K, Ip Mary S M, Chan-Yeung Moira

Abstract excerpt

BACKGROUND: Susceptibility to the development of asthma and other atopic diseases is known to be associated with genetic components. However, association studies with interleukin-4 (IL-4), IL-4 receptor alpha subunit (IL-4R alpha), tumor necrosis factor-alpha (TNF-alpha) and lymphotoxin-alpha (LT-alpha) genes were inconclusive, as both positive and negative results were obtained in several populations studied. We...

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PMID: 17536219
DOI: 10.1159/000103222

Genes

TNF

Variants

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