Article
Effects of Ile164 polymorphism of beta2-adrenergic receptor gene on coronary artery disease.
Journal of the American College of Cardiology - 21 Oct 2008
Piscione Federico, Iaccarino Guido, Galasso Gennaro, Cipolletta Ersilia, Rao Maria Assunta, Brevetti Gregorio, Piccolo Raffaele, Trimarco Bruno, Chiariello Massimo
Abstract excerpt
OBJECTIVES: This study investigated the relationship between beta(2)-adrenergic receptor (B2AR) Ile164 polymorphism and coronary artery disease (CAD). BACKGROUND: B2ARs are crucial to the regulation of vascular tone, and neoangiogenesis is impaired in the presence of isoleucine at position 164 (I...
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