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Article

Ile164 variant of beta2-adrenoceptor does not influence outcome in heart failure but may interact with beta blocker treatment.

European journal of heart failure - 1 Jan 2008

Littlejohn Mathew D, Palmer Barry R, Richards A Mark, Frampton Chris M, Pilbrow Anna P, Troughton Richard W, Cameron Vicky A, Kennedy Martin A

Abstract excerpt

BACKGROUND: The Ile164 variant of the beta2-adrenoceptor has been shown to alter cardiovascular phenotypes and adversely affect survival in heart failure patients. AIMS: We aimed to replicate this observation by genotyping a cohort of 451 heart failure patients for the Ile164 polymorphism. METHODS: Patient outcome was recorded over a median follow-up period of 3.09 years, and genotypes were derived by multiplex...

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Share to Adrenergic beta-Antagonists
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18068431
DOI: 10.1016/j.ejheart.2007.10.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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