Article
Haplotype variation in bovine Toll-like receptor 4 and computational prediction of a positively selected ligand-binding domain.
Proceedings of the National Academy of Sciences of the United States of America - 2 Sept 2003
White Stephen N, Taylor Kristen H, Abbey Colette A, Gill Clare A, Womack James E
Abstract excerpt
Toll-like receptor 4 (TLR4) is a cell-surface receptor that activates innate and adaptive immune responses. Because it recognizes a broad class of pathogen-associated molecular patterns presented by lipopolysaccharides and lipoteichoic acid, TLR4 is a candidate gene for resistance to a large numb...
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