Article
Disparate effects of different mutations in plakoglobin on cell mechanical behavior.
Cell motility and the cytoskeleton - 1 Dec 2008
Huang Hayden, Asimaki Angeliki, Lo Denise, McKenna William, Saffitz Jeffrey
Abstract excerpt
Mutations in genes encoding desmosomal proteins have been implicated in the pathogenesis of heart and skin diseases. This has led to the hypothesis that defective cell-cell adhesion is the underlying cause of injury in tissues that repeatedly bear high mechanical loads. In this study, we examined...
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