Article
The evolution of small insertions and deletions in the coding genes of Drosophila melanogaster.
Molecular biology and evolution - 1 Dec 2013
Chong Zechen, Zhai Weiwei, Li Chunyan, Gao Min, Gong Qiang, Ruan Jue, Li Juan, Jiang Lan, Lv Xuemei, Hungate Eric, Wu Chung-I
Abstract excerpt
Studies of protein evolution have focused on amino acid substitutions with much less systematic analysis on insertion and deletions (indels) in protein coding genes. We hence surveyed 7,500 genes between Drosophila melanogaster and D. simulans, using D. yakuba as an outgroup for this purpose. The evolutionary rate of coding indels is indeed low, at only 3% of that of nonsynonymous substitutions. As coding indels...
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