Article
Notch signaling in pediatric malignancies.
Current oncology reports - 1 Nov 2008
Zweidler-McKay Patrick A
Abstract excerpt
Notch signaling plays crucial roles in many developmental pathways, with Notch mutations linked to several developmental disorders. Because many pediatric malignancies arise from dysregulated development, roles for Notch signaling in these cancers are to be expected. Evidence to support this is now emerging as the Notch pathway is being explored in more pediatric cancers. Not surprisingly, Notch appears to play...
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