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Article

Mutation in pfmdr1 gene in chloroquine-resistant Plasmodium falciparum isolates, Southeast Iran.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Nov 2008

Jalousian Fatemeh, Dalimi Abdolhossein, Samiee Siamak Mirab, Ghaffarifar Fatemeh, Soleymanloo Faramarz, Naghizadeh Ramin

Abstract excerpt

OBJECTIVES: The main objective of the present study was to detect point mutations at positions 86, 184, 1034, 1042, and 1246 of the Plasmodium falciparum multidrug resistance gene (pfmdr1) in blood samples collected from malaria patients in Chabahar, a harbor city located in Southeast Iran. METHODS: Twenty-six blood samples from patients infected with P. falciparum, who had a chloroquine (CQ) response failure,...

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PMID: 18926753
DOI: 10.1016/j.ijid.2008.01.004

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