Article

Clinically Important Alterations in Pharmacogene Expression in Histologically Severe Nonalcoholic Fatty Liver Disease

2022-08-05

Abstract excerpt

<title>Abstract</title> <p>Background Polypharmacy is common in patients with nonalcoholic fatty liver disease (NAFLD) and previous reports suggest that NAFLD is associated with altered drug disposition. This study aimed to determine if patients with histologically severe NAFLD are at risk for altered drug response by characterizing changes in hepatic mRNA expression of genes mediating drug disposition (pharmaco...

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Literature Corpus work: d1f805ca-d4ec-5dbe-af57-ca8c5101d776
DOI: 10.21203/rs.3.rs-1878803/v1

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